Anti-Netrin-1 (Nora-1) Antibody (OAED00371)

Catalog No: OAED00371

Size:100UG

Product Info

• Predicted Species Reactivity: Chicken|Human|Mouse
• Clonality: Monoclonal
• Clone: Nora-1
• Isotype: IgG2a
• Host: Mouse
• Application: Enzyme-linked immunosorbent assay|Immunohistochemistry|Immunoprecipitation|Western blot
• Reconstitution and Storage: Long Term Storage : -20C
  Short Term Storage : +4C
  Handling : After opening, prepare aliquots and store at -20C.
  Avoid freeze/thaw cycles
  Stable for at least 1 year after receipt when stored at -20C.
• Immunogen: Recombinant human, mouse and chicken netrin-1 (aa 28-264).
• Concentration: 1mg/ml
• Specificity: Recognizes human, mouse and chicken netrin-1.
• Source: Purified from concentrated hybridoma tissue culture supernatant.
• Formulation: Liquid. In PBS containing 0.02% sodium azide.
• Purity: ≥95% (SDS-PAGE)
• Application Info: ELISA
  Immunohistochemistry
  Immunoprecipitation (1:100)
  Western Blot (1:1,000)
• Reference: Transfection of human glioma cell lines: U. Naumann; (2011), Full Text
  Spatio-temporal deleted in colorectal cancer (DCC) and netrin-1 expression in human foetal brain development: P.N. Harter, et al.; Neuropathol. Appl. Neurobiol. 36, 623 (2010), Abstract;
  Netrin-1 controls colorectal tumorigenesis by regulating apoptosis: L. Mazelin, et al.; Nature 431, 80 (2004), Abstract;

Target Info

• Gene Symbol: NTN1
• Gene Full Name: netrin 1
• Alias Symbols: epididymis tissue protein Li 131P;MRMV4;netrin 1, mouse, homolog of;netrin-1;NTN1L.
• NCBI Gene Id: 9423
• Protein Name: Netrin-1
• Description of Target: Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serve as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Involved in tumorigenesis by regulating apoptosis.
• Uniprot ID: O95631