Anti-ILEI (Delphy-1) Antibody (OAED00386)

Catalog No: OAED00386

Size:100 ug

Product Info

• Predicted Species Reactivity: Human, Mouse
• Clonality: Monoclonal
• Clone: Delphy-1
• Isotype: IgG2a
• Host: Mouse
• Application: IP, WB
• Reconstitution and Storage: Long Term Storage : -20C
  Short Term Storage : +4C
  Handling : Avoid freeze/thaw cycles.
  Stable for at least 1 year after receipt when stored as recommended.
• Immunogen: Recombinant human ILEI (aa 42-227).
• Concentration: 1mg/ml
• Specificity: Recognizes human and mouse ILEI.
• Source: Purified from concentrated hybridoma tissue culture supernatant.
• Formulation: Liquid. In PBS containing 0.02% sodium azide.
• Purity: Protein G-affinity purified.
  ≥95% (SDS-PAGE)
• Application Info: ELISA
  Immunoprecipitation (1:100)
  Western Blot (1:1,000)
• Reference: ILEI: a cytokine essential for EMT, tumor formation, and late events in metastasis in epithelial cells: T. Waerner, et al.; Cancer Cell 10, 227 (2006), Abstract;
  Cloning, expression, and initial characterization of a novel cytokine-like gene family: Y. Zhu, et al.; Genomics 80, 144 (2002), Abstract;

Target Info

• Gene Symbol: FAM3C
• Alias Symbols: ILEI, GS3786
• NCBI Gene Id: 10447
• Protein Name: Protein FAM3C
• Description of Target: In 2006, T. Waerner, et al. characterized ILEI as a key player in both epithelial to mesenchymal transition and late-stage carcinoma progression. EMT is a process that involves changes in gene expression, cytoskeleton organization, cell adhesion, and extracellular matrix composition. This process is important during tissue formation and organogenesis, but also during cancer progression, metastasis and chronic inflammation. ILEI is overexpressed and/or altered in intracellular localization in multiple human tumors, an event strongly correlated to invasion/EMT, metastasis formation, and survival in human colon and breast cancer.
• Uniprot ID: Q92520