- Description of Target:
- H1FOO may play a key role in the control of gene expression during oogenesis and early embryogenesis, presumably through the perturbation of chromatin structure. H1FOO is essential for meiotic maturation of germinal vesicle-stage oocytes. The somatic type linker histone H1c is rapidly replaced by H1oo in a donor nucleus transplanted into an oocyte. The greater mobility of H1oo as compared to H1c may contribute to this rapid replacement and increased instability of the embryonic chromatin structure. The rapid replacement of H1c with H1oo may play an important role in nuclear remodeling.
- Gene Symbol:
- H1FOO
- Official Gene Full Name:
- H1 histone family, member O, oocyte-specific
- Alias Symbols:
- MGC50807; osH1
- Tissue Tool:
- Find tissues and cell lines supported to express H1FOO.
- Protein Accession# :
- NP_722575
- Nucleotide Accession#:
- NM_153833
- Swissprot Id:
- Q8IZA3
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Protein Size (# AA):
- 346
- Molecular Weight:
- 36kDa
- Application:
- WB
- Immunogen:
- The immunogen for anti-H1FOO antibody: synthetic peptide directed towards the middle region of human H1FOO
- Product Format:
- Lyophilized powder
- Purification:
- Affinity Purified
- Complete computational species homology data:
- H1FOO antibody - middle region (ARP53205_P050)
- Predicted Homology Based on Immunogen Sequence:
- Human: 100%
- Datasheets / Downloads:
- Printable datasheet for
anti-H1FOO antibody
- ARP53205_P050 - Peptide Sequence:
- Synthetic peptide located within the following region: KAPKAGQGPNTKAAAPAKGSGSKVVPAHLSRKTEAPKGPRKAGLPIKASS
- Blocking Peptide:
- For anti-H1FOO antibody is Catalog # AAP53205 (Previous Catalog # AAPP36342)
- Key Reference:
- N/A
- Reconstitution and Storage:
- Add 50 μl of distilled water. Final anti-H1FOO antibody concentration is 1 mg/ml in PBS buffer. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Product Protocols: H1FOO antibody tested with Human Hepg2 Cells (ARP53205_P050)
Aviva Systems Biology is the original manufacturer of this H1FOO antibody (ARP53205_P050)
Click here to view the H1FOO antibody Western Blot Protocol
Product Datasheet Link: H1FOO antibody (ARP53205_P050)
WB Suggested Anti-H1FOO Antibody Titration: 0.2-1 ug/ml
Positive Control: HepG2
Western Blot image: 
Description of Target: H1FOO may play a key role in the control of gene expression during oogenesis and early embryogenesis, presumably through the perturbation of chromatin structure. H1FOO is essential for meiotic maturation of germinal vesicle-stage oocytes. The somatic type linker histone H1c is rapidly replaced by H1oo in a donor nucleus transplanted into an oocyte. The greater mobility of H1oo as compared to H1c may contribute to this rapid replacement and increased instability of the embryonic chromatin structure. The rapid replacement of H1c with H1oo may play an important role in nuclear remodeling.
Questions pertaining to this data can be directed to techsupport@avivasysbio.com
Aviva Systems Biology’s H1FOO antibody (ARP53205_P050) has been tested using other cell lysates and tissues. To obtain more data about this antibody please email us at info@avivasysbio.com.
To order by phone call us at (888) 880-0001, fax us at (858) 552-6975 or send an email to info@avivasysbio.com. Aviva manufactures this antibody so we can offer the best price. Please contact us to request pricing information.
All of Aviva’s products are guaranteed for the applications and experimental sample types mentioned in the datasheet below. Are you curious if this product will work for you? Please contact us at techsupport@avivasysbio.com
- Protocol:
- Tips Information:
See our General FAQ page.
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