Anti-FGF4 Antibody (NT) Polyclonal Antibody (OAAI00448)

Catalog No: OAAI00448

Size:100UG

WB: The full-length recombinant protein of human FGF-4 was blotted by Rabbit anti FGF4 (NT) (cat#OAAI00448) at 1:500. An immunoreactive band is observed ~22 kDa.

Product Info

• Predicted Species Reactivity: Human|Mouse|Rat
• Product Format: Liquid. This affinity purified antibody is supplied in sterile Phosphatebuffered saline (pH7.2) containing antibody stabilizer
• Clonality: Polyclonal
• Isotype: Rabbit IgG
• Host: Rabbit
• Application: Enzyme-linked immunosorbent assay|Flow cytometry|Immunohistochemistry|Immunoprecipitation|Western blot
• Additional Information: Background: FGF4 is a member of fibroblast growth factor (FGF) family. The FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its oncogenic transforming activity. FGF4and FGF3, another oncogenic growth factor, are located closely on chromosome 11. Co-amplification of both genes was found in various kinds of human tumors. Studies on the mouse homolog suggested a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway.
  Positive Control: Recombinant protein FGF-4
  Cellular Location: Secreted.
• Reconstitution and Storage: The antibodies are stable for 24 months from date of receipt when stored at -20C to -70C. The antibodies can be stored at 2C-8C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
• Immunogen: A synthetic peptide corresponding to the N-terminus of Fibroblast Growth Factor 4 protein. This sequence is identical to human, mouse, rat and bovine.
• Purification: Affinity Purified
• Concentration: 100ug/200ul
• Specificity: FGF4
• Formulation: This affinity purified antibody is supplied in sterile Phosphatebuffered saline (pH7.2) containing antibody stabilizer
• Application Info: WB: 0.1-1 ug/ml | ELISA: 0.01-0.1 ug/ml | IP: 2-5 ug/ml | IHC: 2-10 ug/ml | FC: Not tested
• Reference: Ma,Y.G., Rosfjord,E., Huebert,C., Wilder,P., Tiesman,J., Kelly,D. and Rizzino,A. Transcriptional regulation of the murine k-FGF gene in embryonic cell lines. Dev. Biol. 154 (1), 45-54 (1992)

Target Info

• Gene Symbol: FGF4
• Gene Full Name: fibroblast growth factor 4
• Alias Symbols: FGF-4;fibroblast growth factor 4;HBGF-4;heparin secretory transforming protein 1;heparin-binding growth factor 4;HST;HST-1;HSTF1;HSTF-1;human stomach cancer, transforming factor from FGF-related oncogene;kaposi sarcoma oncogene;KFGF;K-FGF;oncogene HST;transforming protein KS3.
• NCBI Gene Id: 2249
• Description of Target: FGF4 is a member of fibroblast growth factor (FGF) family. The FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its oncogenic transforming activity.
  FGF4and FGF3, another oncogenic growth factor, are located closely on chromosome 11. Co-amplification of both genes was found in various kinds of Human tumors. Studies on the Mouse homolog sμggested a function in bone morphogenesis and limb development throμgh the sonic hedgehog (SHH) signaling pathway.
  
• Uniprot ID: P08620
• Molecular Weight: 22