Anti-Caspase-9 (10-1-87) Antibody (OAED00020)

Catalog No: OAED00020

Size:100 ug

Western blot analysis of MW marker (1), Jurkat (2), and Jurkat + staurosporine (3) cells probed with Caspase 9 mAb (10-1-87).

Product Info

• Predicted Species Reactivity: Human
• Clonality: Monoclonal
• Clone: 10-1-87
• Isotype: IgG2a
• Host: Mouse
• Application: WB
• Reconstitution and Storage: Long Term Storage : -20C
  
• Immunogen: Recombinant full length human Caspase-9.
• Specificity: Recognizes human caspase-9. Detects bands of ~47kDa (full length) and ~37/35kDa (cleaved) by Western blot.
• Formulation: Liquid. In PBS, pH 7.2, containing 0.09% sodium azide and 50% glycerol.
• Purity: Protein G affinity purified.
  
• Application Info: Western Blot (1μg/ml, ECL)
  Optimal conditions must be determined individually for each application.

Target Info

• Gene Symbol: CASP9
• Alias Symbols: MCH6, APAF3, APAF-3, PPP1R56, ICE-LAP6
• NCBI Gene Id: 842
• Protein Name: Caspase-9
• Description of Target: The caspases are a family of cysteine proteases that cleave after certain aspartate residues, and are primarily recognized as mediators of apoptosis. caspases are synthesized as inactive zymogens that can be cleaved to form active enzymes following the induction of apoptosis by stress or death receptors. Initiator caspases (e.g. caspase-8 and -10) are activated by dimerization of the zymogen on a dedicated adaptor protein. These activated initiator caspases in-turn cleave downstream effector or executioner caspases (e.g. caspase-3, -6, and -7) in a cascade-like manner, which cleave key cellular proteins that lead to the morphological changes associated with apoptotic cell death.
• Uniprot ID: P55211