- Description of Target:
- This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes.
- Gene Symbol:
- ADRB2
- Alias Symbols:
- BAR; B2AR; ADRBR; ADRB2R; BETA2AR
- Protein Accession# :
- NP_000015
- Nucleotide Accession#:
- NM_000024
- Swissprot Id:
- P07550
- Tag:
- GST
- Quality Control:
- This product was tested on western blot.
- Reconstitution and Storage:
- Add 100ul of distilled water. Final concentration is 1 mg/ml. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
- Additional Information:
- Buffer Formulation: 0.1M Tris-HCl (pH 6.8) buffer containing 0.2M DTT, 4% SDS, 0.2% Bromophenol blue and 20% Sucrose.
- Key Reference:
- N/A
- Datasheets / Downloads:
- APL10541
- Protocol:
- Tips Information:
See our General FAQ page.


