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100 ul
$289.00
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ADD3 antibody - C-terminal region (ARP59946_P050)

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Gene Symbol:
ADD3
NCBI Gene Id:
120
Official Gene Full Name:
Adducin 3 (gamma)
Protein Name:
Gamma-adducin
Swissprot Id:
Q9UEY8
Protein Accession #:
NP_001112
Nucleotide Accession #:
NM_001121
Alias Symbols:
ADDL
Description of Target:
Adducins are heteromeric proteins composed of different subunits referred to as adducin alpha, beta and gamma. The three subunits are encoded by distinct genes and belong to a family of membrane skeletal proteins involved in the assembly of spectrin-actin network in erythrocytes and at sites of cell-cell contact in epithelial tissues. Polymorphisms resulting in amino acid substitutions in these two subunits have been associated with the regulation of blood pressure in an animal model of hypertension. Heterodimers consisting of alpha and gamma subunits have also been described. Structurally, each subunit is comprised of two distinct domains.
Protein Size (# AA):
706
Molecular Weight:
78kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity Purified
Application:
IF, WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express ADD3.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express ADD3.
Immunogen:
The immunogen is a synthetic peptide directed towards the C terminal region of human ADD3
Species Reactivity:
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
Predicted Homology Based on Immunogen Sequence:
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
Complete computational species homology data:
Anti-ADD3 (ARP59946_P050)
Peptide Sequence:
Synthetic peptide located within the following region: DELAKRVSRLSTSTTIENIEITIKSPEKIEEVLSPEGSPSKSPSKKKKKF
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Protein Interactions:
UBC; RNF2; HDAC8; ATXN1; SUMO1; PRKCA;
Blocking Peptide:
For anti-ADD3 (ARP59946_P050) antibody is Catalog # AAP59946 (Previous Catalog # AAPP46109)
Datasheets / Downloads:
Printable datasheet for anti-ADD3 (ARP59946_P050) antibody

Customer Reviews for ADD3 Antibody (ARP59946_P050) tested with mouse auditory cells in Immunofluorescence

CAT# ARP59946_P050

ADD3 antibody

ADD3 antibody Immunofluorescence

submitted by:
Dr. Channy Park
CB&G House Research Institute

Product Protocols: ADD3 antibody tested with Human Thp-1 Cells (ARP59946_P050)

Aviva Systems Biology is the original manufacturer of this ADD3 antibody (ARP59946_P050)

Click here to view the ADD3 antibody Western Blot Protocol

Product Datasheet Link: ADD3 antibody (ARP59946_P050)

WB Suggested Anti-ADD3 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: THP-1

Western Blot image:


Description of Target: Adducins are heteromeric proteins composed of different subunits referred to as adducin alpha, beta and gamma. The three subunits are encoded by distinct genes and belong to a family of membrane skeletal proteins involved in the assembly of spectrin-actin network in erythrocytes and at sites of cell-cell contact in epithelial tissues. Polymorphisms resulting in amino acid substitutions in these two subunits have been associated with the regulation of blood pressure in an animal model of hypertension. Heterodimers consisting of alpha and gamma subunits have also been described. Structurally, each subunit is comprised of two distinct domains.

Questions pertaining to this data can be directed to techsupport@avivasysbio.com

Aviva Systems Biology’s ADD3 antibody (ARP59946_P050) has been tested using other cell lysates and tissues. To obtain more data about this antibody please email us at info@avivasysbio.com.

To order by phone call us at (888) 880-0001, fax us at (858) 552-6975 or send an email to info@avivasysbio.com. Aviva manufactures this antibody so we can offer the best price. Please contact us to request pricing information.

All of Aviva’s products are guaranteed for the applications and experimental sample types mentioned in the datasheet below. Are you curious if this product will work for you? Please contact us at techsupport@avivasysbio.com

 
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