Catalog No: ARP56302_P050
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ARP56302_P050
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Datasheets/ManualsPrintable datasheet for anti-ACO2 (ARP56302_P050) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Rat, Cow, Pig, Yeast
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationIHC, WB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the C terminal region of human ACO2
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 100%; Human: 100%; Pig: 100%; Rat: 100%; Yeast: 100%
Peptide SequenceSynthetic peptide located within the following region: RYYKKHGIRWVVIGDENYGEGSSREHAALEPRHLGGRAIITKSFARIHET
Concentration0.5 mg/ml
Blocking PeptideFor anti-ACO2 (ARP56302_P050) antibody is Catalog # AAP56302 (Previous Catalog # AAPP34418)
Sample Type Confirmation

ACO2 is strongly supported by BioGPS gene expression data to be expressed in 721_B

Publications

Scheving, R. et al. Protein S-nitrosylation and denitrosylation in the mouse spinal cord upon injury of the sciatic nerve. J. Proteomics 75, 3987-4004 (2012). 22588120

Gene SymbolACO2
Gene Full NameAconitase 2, mitochondrial
Alias SymbolsICRD, OCA8, OPA9, ACONM, HEL-S-284
NCBI Gene Id50
Protein NameAconitate hydratase, mitochondrial
Description of TargetACO2 belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15(PRSS15), also known as Lon protease, after oxidative modification.
Uniprot IDQ99798
Protein Accession #NP_001089
Nucleotide Accession #NM_001098
Protein Size (# AA)780
Molecular Weight82kDa
Protein InteractionsSUMO2; UBC; SUMO1; NEDD8; MDM2; ASB9; VCAM1; ITGA4; AK3; SIN3A; ACAA2; APP; ACAT1; ATXN1L; SUMO4; PSMD4; SRRM2;
  1. What is the species homology for "ACO2 Antibody - C-terminal region (ARP56302_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Rat, Cow, Pig, Yeast".

  2. How long will it take to receive "ACO2 Antibody - C-terminal region (ARP56302_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "ACO2 Antibody - C-terminal region (ARP56302_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "ACO2 Antibody - C-terminal region (ARP56302_P050)"?

    This target may also be called "ICRD, OCA8, OPA9, ACONM, HEL-S-284" in publications.

  5. What is the shipping cost for "ACO2 Antibody - C-terminal region (ARP56302_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "ACO2 Antibody - C-terminal region (ARP56302_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "ACO2 Antibody - C-terminal region (ARP56302_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "82kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "ACO2 Antibody - C-terminal region (ARP56302_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "ACO2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "ACO2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "ACO2"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "ACO2"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "ACO2"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "ACO2"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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