- Description of Target:
- ABI2 may act in regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. ABI2 is a part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. It regulates ABL1/c-Abl-mediated phosphorylation of MENA.
- Gene Symbol:
- ABI2
- Alias Symbols:
- ABI-2; ABI2B; AIP-1; AblBP3; SSH3BP2; argBPIA; argBPIB
- Tissue Tool:
- Find tissues and cell lines supported to express ABI2.

- Protein Accession# :
- NP_005750
- Nucleotide Accession#:
- NM_005759
- Swissprot Id:
- Q9NYB9
- Host:
- Rabbit
- Protein Size (# AA):
- 475
- Molecular Weight:
- 52kDa
- Application:
- WB
- Partner Proteins:
- ADAM19,ABL1,CCDC53,ENAH,IFT20,KRT15,KRT19,KRT20,NCK2,PCM1,SH3KBP1,SNAP23,VCL,VPS37C,WASF2,ABL1,ADAM19,CCDC53,IFT20,KRT15,KRT19,KRT20,NCK2,PCM1,SH3KBP1,SNAP23,TRAF3IP1,TRIM32,UBC,VCL
- Immunogen:
- The immunogen for Anti-ABI2 antibody is: synthetic peptide directed towards the N-terminal region of Human ABI2
- Product Format:
- Lyophilized powder
- Complete computational species homology data:
- ABI2 Antibody - N-terminal region (ARP61420_P050)
- Datasheets / Downloads:
- Printable datasheet for
anti-ABI2 antibody
ARP61420_P050 - Peptide Sequence:
- Synthetic peptide located within the following region: MLLEEEIPGGRRALFDSYTNLERVADYCENNYIQSADKQRALEETKAYTT
- Blocking Peptide:
- Catalog # AAP61420
- Key Reference:
- N/A
- Reconstitution and Storage:
- Add 50 μl of distilled water. Final Anti-ABI2 antibody concentration is 1 mg/ml in PBS buffer. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
- Protocol:
- Tips Information:
See our General FAQ page.


