Catalog No: OAAN01179
Price: $0.00
SKU
OAAN01179
Availability: Domestic: within 1-2 weeks delivery | International: 1-2 weeks
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Datasheets/ManualsPrintable datasheet for anti-ABAT (OAAN01179)
Product Info
Predicted Species ReactivityHuman, Mouse, Rat
Product FormatLiquid
ClonalityPolyclonal
IsotypeIgG
HostRabbit
ConjugationUnconjugated
ApplicationWB, IHC, IF
Reconstitution and StorageStore at -20C. Avoid repeated freeze/thaw cycles.
ImmunogenRecombinant protein of human ABAT
PurificationAffinity purified against immunogen
Preservative0.02% Sodium Azide
Application InfoWB: 1:500 - 1:2,000. IHC: 1:50 - 1:200. IF: 1:50 - 1:200
Storage BufferPBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Gene SymbolABAT
Gene Full Name4-aminobutyrate aminotransferase
Alias SymbolsGABAT, NPD009, GABA-AT
NCBI Gene Id18
Protein Name4-aminobutyrate aminotransferase, mitochondrial
Description of Target4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5-phosphate. The protein sequence is over 95% similar to the pig protein. GABA is estimated to be present in nearly one-third of human synapses. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.
Uniprot IDP80404
Protein Accession #NP_000654.2
Nucleotide Accession #NM_000663.4
Molecular Weight56 kDa
  1. What is the species homology for "ABAT Antibody (OAAN01179)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat".

  2. How long will it take to receive "ABAT Antibody (OAAN01179)"?

    This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".

  3. What buffer format is "ABAT Antibody (OAAN01179)" provided in?

    This item is provided in "Liquid".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "ABAT Antibody (OAAN01179)"?

    This target may also be called "GABAT, NPD009, GABA-AT" in publications.

  5. What is the shipping cost for "ABAT Antibody (OAAN01179)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "ABAT Antibody (OAAN01179)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "ABAT Antibody (OAAN01179)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "56 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "ABAT Antibody (OAAN01179)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "ABAT"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "ABAT"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "ABAT"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "ABAT"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "ABAT"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "ABAT"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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