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Catalog No: ARP40370_P050
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ARP40370_P050
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Datasheets/ManualsPrintable datasheet for anti-AARS (ARP40370_P050) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB, IHC
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the N terminal region of human AARS
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 86%; Rabbit: 100%; Rat: 100%; Zebrafish: 79%
Peptide SequenceSynthetic peptide located within the following region: DSTLTASEIRQRFIDFFKRNEHTYVHSSATIPLDDPTLLFANAGMNQFKP
Concentration0.5 mg/ml
Blocking PeptideFor anti-AARS (ARP40370_P050) antibody is Catalog # AAP40370 (Previous Catalog # AAPP22114)
Sample Type Confirmation

AARS is supported by BioGPS gene expression data to be expressed in HEK293T

ReferenceOlsen,J.V., (2006) Cell 127 (3), 635-648
Gene SymbolAARS
Gene Full NameAlanyl-tRNA synthetase
Alias SymbolsAARS, CMT2N, DEE29, EIEE29
NCBI Gene Id16
Protein NameAlanine--tRNA ligase, cytoplasmic
Description of TargetThe human alanyl-tRNA synthetase (AARS) belongs to a family of tRNA synthases, of the class II enzymes. Class II tRNA synthases evolved early in evolution and are highly conserved. This is reflected by the fact that 498 of the 968-residue polypeptide human AARS shares 41% identity witht the E.coli protein. tRNA synthases are the enzymes that interpret the RNA code and attach specific aminoacids to the tRNAs that contain the cognate trinucleotide anticodons. They consist of a catalytic domain which interacts with the amino acid acceptor-T psi C helix of the tRNA, and a second domain which interacts with the rest of the tRNA structure. The human alanyl-tRNA synthetase (AARS) belongs to a family of tRNA synthases, of the class II enzymes. Class II tRNA synthases evolved early in evolution and are highly conserved. This is reflected by the fact that 498 of the 968-residue polypeptide human AARS shares 41% identity witht the E.coli protein. tRNA synthases are the enzymes that interpret the RNA code and attach specific aminoacids to the tRNAs that contain the cognate trinucleotide anticodons. They consist of a catalytic domain which interacts with the amino acid acceptor-T psi C helix of the tRNA, and a second domain which interacts with the rest of the tRNA structure.
Uniprot IDP49588
Protein Accession #NP_001596
Nucleotide Accession #NM_001605
Protein Size (# AA)968
Molecular Weight107kDa
Protein InteractionsISG15; UBC; SUMO2; SUMO1; NEDD8; TPD52; STAT5B; SRP9; PPP2R5E; METTL1; HSF1; CALU; DPP9; NIF3L1; ANKMY2; DPP8; IPO11; EEF2K; CACYBP; ARPC1B; SAE1; TOM1L1; EIF4A3; WARS; TPD52L2; UBD; VCAM1; ITGA4; HSP90AB1; HSP90AA1; FN1; NSUN2; LARS; FARSB; UBA1; QARS; N
  1. What is the species homology for "AARS Antibody - N-terminal region (ARP40370_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish".

  2. How long will it take to receive "AARS Antibody - N-terminal region (ARP40370_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "AARS Antibody - N-terminal region (ARP40370_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "AARS Antibody - N-terminal region (ARP40370_P050)"?

    This target may also be called "AARS, CMT2N, DEE29, EIEE29" in publications.

  5. What is the shipping cost for "AARS Antibody - N-terminal region (ARP40370_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "AARS Antibody - N-terminal region (ARP40370_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "AARS Antibody - N-terminal region (ARP40370_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "107kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "AARS Antibody - N-terminal region (ARP40370_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "AARS"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "AARS"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "AARS"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "AARS"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "AARS"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "AARS"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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